Revisiting the Syndrome of “Obsessional Slowness”

Classification and treatment of obsessional slowness.

Obsessional slowness is regarded as an uncommon but severely disabling variant of obsessive-compulsive disorder. This paper examines the psychopathology, classification, pathophysiology and treatment of obsessional slowness. It argues that primary obsessional slowness does not require classification as a separate syndrome because it can be found to be secondary to recognised phenomena of obsess...

Revisiting Beta 2 Glycoprotein I, the Major Autoantigen in the Antiphospholipid Syndrome

Beta 2 glycoprotein I (β2GPI) is a single chain 50 kDa highly glycosylated glycoprotein at an approximate concentration of 4 μM in cells. The abundance of this protein in plasma and its high state of preservation indicate the important role of this protein in mammalian. In addition, β2GPI has a particular structure in the fifth domain, and is categorized as the major antigen recognized by autoa...

Revisiting Plummer Vinson Syndrome

Plummer Vinson syndrome is a rare association of postcricoid dysphagia, upper esophageal webs, and iron deficiency anemia. Iron deficiency state has been hypothesized to play an etiological role. While literature review elucidates the resolution of dysphagia in most cases with iron therapy, we discuss our case where the dysphagia was resistant to such therapy and necessitated a mechanical dilat...

Slowness Surface Wave Surface

Slowness in schizophrenia.

Nufferno Speed Test In this investigation we have used only the Nufferno speed test, which is designed to measure speed as distinct from general level of intelligence. It consists of 19 problems of the Thurstone letterseries type in each of which the patient is presented with series of letters and is required to add at the end of the series the letter which is appropriate to the sequence (Furne...